Pub. Date : 2018 Jan 1
PMID : 29030066
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Etoposide induced NMI promotes cell apoptosis by activating the ARF-p53 signaling pathway in lung carcinoma. | Etoposide | tumor protein p53 | Homo sapiens |
2 | Furthermore, etoposide treatment up-regulates the expression of NMI and ARF, enhances the interaction of NMI and ARF and promotes the p53 transcriptional activities. | Etoposide | tumor protein p53 | Homo sapiens |
3 | These investigations demonstrated etoposide-induced NMI can suppress tumor proliferation and promote cell apoptosis by activating the ARF-p53 signaling pathway in lung carcinoma. | Etoposide | tumor protein p53 | Homo sapiens |