Pub. Date : 2018 Aug
PMID : 29025387
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In Vitro Study on Influences of UGT1A8 Gene Polymorphisms on Mycophenolate Mofetil Metabolism. | Mycophenolic Acid | UDP glucuronosyltransferase family 1 member A8 | Homo sapiens |
| 2 | The UDP glucuronosyltransferase enzyme is the key metabolic enzyme for mycophenolate mofetil, and UGT1A8 gene polymorphisms may affect the elimination of mycophenolate mofetil in patients. | Mycophenolic Acid | UDP glucuronosyltransferase family 1 member A8 | Homo sapiens |
| 3 | Here, we conducted an in vitro study to explore the relation between UGT1A8 gene polymorphisms and mycophenolate mofetil metabolism. | Mycophenolic Acid | UDP glucuronosyltransferase family 1 member A8 | Homo sapiens |
| 4 | CONCLUSIONS: Our results showed that UGT1A8 gene polymorphisms can affect the activity of UDP glucuronosyltransferase enzyme, which may influence the elimination of mycophenolate mofetil in different patients. | Mycophenolic Acid | UDP glucuronosyltransferase family 1 member A8 | Homo sapiens |