Title : Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells.

Pub. Date : 2017 Oct 9

PMID : 28991260






1 Functional Relationships(s)
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1 We demonstrate that TIS Cal51 cells treated with 75 nM PTX for 7 days became senescent (senescence-associated beta-galactosidase (SA-beta-Gal) positive, Ki67-negative, increased p21 and p16, G2/M cell cycle arrest) and released significantly more EVs (P=0.0002) and exosomes (P=0.0007) than non-senescent control cells. Paclitaxel H3 histone pseudogene 16 Homo sapiens