Title : Effects of Genetic Variants on Carboxylesterase 1 Gene Expression, and Clopidogrel Pharmacokinetics and Antiplatelet Effects.

Pub. Date : 2018 Mar

PMID : 28990360






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Conversely, the CES1 c.428G>A missense SNV (rs71647871) impaired the hydrolysis of clopidogrel, increased exposure to clopidogrel active metabolite and enhanced its antiplatelet effects. Clopidogrel carboxylesterase 1 Homo sapiens
2 Conversely, the CES1 c.428G>A missense SNV (rs71647871) impaired the hydrolysis of clopidogrel, increased exposure to clopidogrel active metabolite and enhanced its antiplatelet effects. Clopidogrel carboxylesterase 1 Homo sapiens