Title : Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming.

Pub. Date : 2017 Sep 15

PMID : 28978059






1 Functional Relationships(s)
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1 Targeting 6PGD and NADPH production was sufficient to block growth of AML cell lines resistant to the chemotherapeutics daunorubicin and cytarabine. Daunorubicin phosphogluconate dehydrogenase Homo sapiens