Title : Phosphorylation of p38 in Trigeminal Ganglion Neurons Contributes to Tongue Heat Hypersensitivity in Mice.

Pub. Date : 2017 Fall

PMID : 28973050






2 Functional Relationships(s)
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1 RESULTS: TNBS application to the tongue induced noninflammatory heat hypersensitivity accompanied by the enhancement of p38 phosphorylation in TG neurons innervating the tongue and by an increase in the number of TRPV1 and pp38-immunoreactive (IR) TG neurons innervating the tongue. Trinitrobenzenesulfonic Acid mitogen-activated protein kinase 14 Mus musculus
2 CONCLUSION: p38 signaling cascades are involved in tongue heat hyperalgesia in association with TRPV1 upregulation in TG neurons innervating the TNBS-treated tongue. Trinitrobenzenesulfonic Acid mitogen-activated protein kinase 14 Mus musculus