Title : Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence.

Pub. Date : 2018 Sep

PMID : 28972577






1 Functional Relationships(s)
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1 In this largest-ever GWAS meta-analysis for nicotine dependence and the largest-ever cross-ancestry GWAS meta-analysis for any smoking phenotype, we reconfirmed the well-known CHRNA5-CHRNA3-CHRNB4 genes and further yielded a novel association in the DNA methyltransferase gene DNMT3B. Nicotine cholinergic receptor nicotinic alpha 3 subunit Homo sapiens