Title : Role of myeloperoxidase in abdominal aortic aneurysm formation: mitigation by taurine.

Pub. Date : 2017 Dec 1

PMID : 28971841






1 Functional Relationships(s)
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1 Oral administration of taurine [1% or 4% (wt/vol) in drinking water], an amino acid known to react rapidly with MPO-generated oxidants like hypochlorous acid, also prevented AAA formation in the ANG II and elastase models as well as the CaCl2 application model of AAA formation while reducing aortic peroxidase activity and aortic protein-bound dityrosine levels, an oxidative cross link formed by MPO. Water myeloperoxidase Homo sapiens