Pub. Date : 2017 Sep
PMID : 28970848
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Crotonis Fructus Extract Inhibits 12-O-Tetradecanoylphorbol-13-Acetate-Induced Expression of Matrix Metalloproteinase-9 via the Activator Protein-1 Pathway in MCF-7 Cells. | Tetradecanoylphorbol Acetate | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | Furthermore, CFE attenuated the TPA-induced activation of AP-1. | Tetradecanoylphorbol Acetate | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 3 | CONCLUSION: The results indicated that the inhibitory effects of CFE against TPA-induced MMP-9 expression and MCF-7 cell invasion were dependent on the protein kinase C delta/p38/c-Jun N-terminal kinase/AP-1 pathway. | Tetradecanoylphorbol Acetate | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |