Title : The PPARγ agonist rosiglitazone promotes the induction of brite adipocytes, increasing β-adrenoceptor-mediated mitochondrial function and glucose uptake.

Pub. Date : 2018 Jan

PMID : 28970184






2 Functional Relationships(s)
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1 Treatment of brown adipocytes with rosiglitazone increases uncoupling protein 1 (UCP1) levels, and increases beta3-adrenoceptor mitochondrial function but does not affect glucose uptake responses. Rosiglitazone uncoupling protein 1 (mitochondrial, proton carrier) Mus musculus
2 In contrast, inguinal white adipocytes only express UCP1 and beta3-adrenoceptors following rosiglitazone treatment, which results in an increase in all beta3-adrenoceptor-mediated functions. Rosiglitazone uncoupling protein 1 (mitochondrial, proton carrier) Mus musculus