Title : In vitro metabolism of 4, 5-dimethoxycanthin-6-one by human liver microsomes and its inhibition on human CYP1A2.

Pub. Date : 2017 Dec 1

PMID : 28962866






1 Functional Relationships(s)
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1 Furthermore, the present work found that DCO uncompetitively inhibited CYP1A2-mediated phenacetin O-deethylation with an IC50 value of 1.7muM and a Ki value of 2.6muM. Phenacetin cytochrome P450 family 1 subfamily A member 2 Homo sapiens