Pub. Date : 2017
PMID : 28955006
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phase I/II study of alectinib in lung cancer with RET fusion gene: study protocol. | alectinib | ret proto-oncogene | Homo sapiens |
| 2 | Alectinib is an approved anaplastic lymphoma kinase (ALK) inhibitor that may also be effective for RET fusion-positive NSCLC. | alectinib | ret proto-oncogene | Homo sapiens |
| 3 | CONCLUSION: This is the first study to investigate the safety and preliminary efficacy of alectinib in RET fusion-positive NSCLC patients. | alectinib | ret proto-oncogene | Homo sapiens |
| 4 | If successful, alectinib treatment may lead to substantial and important changes in the management of NSCLC with RET fusion genes. | alectinib | ret proto-oncogene | Homo sapiens |