Pub. Date : 2017 Oct
PMID : 28943944
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Andrographolide suppresses proliferation of human colon cancer SW620 cells through the TLR4/NF-kappaB/MMP-9 signaling pathway. | andrographolide | matrix metallopeptidase 9 | Homo sapiens |
| 2 | The present study investigated whether andrographolide suppresses the proliferation of human colon cancer cell through the Toll-like receptor 4 (TLR4)/nuclear factor (NF)-kappaB/matrix metalloproteinase-9 (MMP-9) signaling pathway. | andrographolide | matrix metallopeptidase 9 | Homo sapiens |
| 3 | The results revealed that the anti-proliferation effects of andrographolide on the SW620 cells was associated with the inhibition of TLR4, MyD88, NF-kappaB-p65 and MMP-9 signaling activation. | andrographolide | matrix metallopeptidase 9 | Homo sapiens |
| 4 | The results suggest that andrographolide is a promising drug for treatment of human colon cancer via suppression of the TLR4/NF-kappaB/MMP-9 signaling pathway. | andrographolide | matrix metallopeptidase 9 | Homo sapiens |