Pub. Date : 1987
PMID : 2894222
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In vitro studies with pindolol show that its maximum stimulant action is similar to that of isoprenaline in tissues possessing mainly beta 2-adrenoceptors, but is negligible in tissues possessing mainly beta 1-adrenoceptors. | Pindolol | potassium calcium-activated channel subfamily M regulatory beta subunit 2 | Homo sapiens |
| 2 | In man the arteriodilator effects observed after intra-arterially infused pindolol at concentrations within the same range as those producing an antihypertensive effect also suggest a stimulant action on vascular beta 2-adrenoceptors. | Pindolol | potassium calcium-activated channel subfamily M regulatory beta subunit 2 | Homo sapiens |
| 3 | The evidence available therefore suggests that although pindolol blocks both beta 1- and beta 2-subtypes, it selectively stimulates beta 2-adrenoceptors. | Pindolol | potassium calcium-activated channel subfamily M regulatory beta subunit 2 | Homo sapiens |