Title : Backbone resonance assignment of the human uracil DNA glycosylase-2.

Pub. Date : 2018 Apr

PMID : 28940147






1 Functional Relationships(s)
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1 We have performed the structural study of UNG2 by NMR and we report its (1HN, 15N, 13Calpha, 13Cbeta and 13C") chemical shift backbone assignment and its secondary structure in solution as predicted by TALOS-N. We aim to determine with accuracy by NMR, the residues of UNG2 interacting with Vpr, characterize their interaction and use the local structure of UNG2 and its interface with Vpr to propose potential ligands disturbing this interaction. 13cbeta uracil DNA glycosylase Homo sapiens