Title : CoQ0-induced mitochondrial PTP opening triggers apoptosis via ROS-mediated VDAC1 upregulation in HL-60 leukemia cells and suppresses tumor growth in athymic nude mice/xenografted nude mice.

Pub. Date : 2018 Jan

PMID : 28918503






1 Functional Relationships(s)
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1 The activation of p-GSK3beta expression, cyclophilin D inhibition, and p53 activation through ROS are involved in CoQ0-induced HL-60 apoptotic cell death. ros tumor protein p53 Homo sapiens