Title : Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.

Pub. Date : 2017 Oct 10

PMID : 28904078






2 Functional Relationships(s)
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1 Our results further emphasize the role of P450-P450 interactions in regulatory cross-talk in human drug-metabolizing ensemble and suggest a role of interactions of CYP2E1 with CYP2D6 in pharmacologically important instances of alcohol-drug interactions. Alcohols cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 Our results further emphasize the role of P450-P450 interactions in regulatory cross-talk in human drug-metabolizing ensemble and suggest a role of interactions of CYP2E1 with CYP2D6 in pharmacologically important instances of alcohol-drug interactions. Alcohols cytochrome P450 family 2 subfamily B member 6 Homo sapiens