Title : Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer.

Pub. Date : 2017 Aug 15

PMID : 28903368






1 Functional Relationships(s)
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1 Functional autophagy was demonstrated in CC cell lines (LoVo; HT-29) showing a dose-dependent increase of the autophagy markers LC3B, p62 and autophagic vesciles upon increasing concentrations of the autophagy inhibitor chloroquine, which was demonstrated by immunoblotting, immunofluorescence and electron microscopy. Chloroquine microtubule associated protein 1 light chain 3 beta Homo sapiens