Title : Mesalazine tolerance in patients with inflammatory bowel disease and previous intolerance or allergy to sulphasalazine or sulphonamides.

Pub. Date : 1987 Sep

PMID : 2890198






3 Functional Relationships(s)
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1 Fifty patients intolerant of or allergic to sulphasalazine (SASP) or sulphonamides were treated with mesalazine. Mesalamine aspartic peptidase retroviral like 1 Homo sapiens
2 The patients with allergic reactions, including rash, fever, and systemic manifestations from SASP, were most likely to be intolerant of or allergic to mesalazine (four of seven patients); two of them developed a similar reaction from both SASP and mesalazine. Mesalamine aspartic peptidase retroviral like 1 Homo sapiens
3 Patients with severe allergic reactions with systemic manifestations from SASP should be treated with caution with 5-aminosalicylic acid preparations. Mesalamine aspartic peptidase retroviral like 1 Homo sapiens