Title : In Vitro Comparison of the Role of P-Glycoprotein and Breast Cancer Resistance Protein on Direct Oral Anticoagulants Disposition.

Pub. Date : 2018 Apr

PMID : 28895074






1 Functional Relationships(s)
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1 CONCLUSION: This study allowed identification of three different profiles of ABC carrier-mediated transport: predominantly P-gp-dependent transport (dabigatran), preferential BCRP-dependent transport (apixaban) and approximately equivalent P-gp and BCRP-mediated transport (edoxaban and rivaroxaban). edoxaban ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens