Title : Characterization of the activity of a platelet activating factor antagonist, CV-3988.

Pub. Date : 1987 Jun

PMID : 2888915






1 Functional Relationships(s)
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1 The inhibition was shown to be specific and competitive with PAF on its receptor by the following observations: parallel shift of the dose-response curve; crossing of double reciprocal plots on the intersection of the ordinate; and no inhibition on other autacoids such as bradykinin, histamine, 5-hydroxytryptamine and LTC4. Leukotriene C4 PCNA clamp associated factor Rattus norvegicus