Pub. Date : 2017 Sep 8
PMID : 28886730
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Annexin A2 contributes to cisplatin resistance by activation of JNK-p53 pathway in non-small cell lung cancer cells. | Cisplatin | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | CONCLUSIONS: These data suggested that Annexin A2 induces cisplatin resistance of NSCLCs via regulation of JNK/c-Jun/p53 signaling, and provided an evidence that blockade of Annexin A2 could serve as a novel therapeutic approach for overcoming drug resistance in NSCLCs. | Cisplatin | mitogen-activated protein kinase 8 | Homo sapiens |