Title : [Mechanisms for the regulatory effect of prostaglandin E2/prostaglandin E receptor 4 on high mobility group box-1 protein in lipopolysaccharide-induced sepsis in mouse peritoneal macrophage].

Pub. Date : 2017 Aug 28

PMID : 28872079






1 Functional Relationships(s)
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1 : Conclusion: PGE2 can up-regulate the expression of HMGB1 in sepsis of peritoneal macrophages through EP4 receptor, which may be related to the activation of EGFR/PI3K/Akt signaling pathway. Dinoprostone prostaglandin E receptor 4 (subtype EP4) Mus musculus