Title : Assay of DNA methyltransferase 1 activity based on uracil-specific excision reagent digestion induced G-quadruplex formation.

Pub. Date : 2017 Sep 15

PMID : 28870318






1 Functional Relationships(s)
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1 Furthermore, the inhibition assay study demonstrates that SGI-1027 can inhibit the DNMT 1 activity with the IC50 values of 6 muM in the presence of 160 muM S-adenosylmethionine. S-Adenosylmethionine DNA methyltransferase 1 Homo sapiens