Title : Acetylenic derivative of betulin induces apoptosis in endometrial adenocarcinoma cell line.

Pub. Date : 2017 Nov

PMID : 28863383






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Previous studies suggested that this group of compounds affect prolidase activity (proline releasing enzyme from imidodipeptides) and collagen biosynthesis (proline utilizing process) providing substrate (proline) for proline oxidase (POX) dependent apoptosis. Proline peptidase D Homo sapiens
2 The data suggest that massive production of proline by proBet-dependent activation of prolidase and inhibition of proline utilization for collagen biosynthesis may represent mechanism for POX-dependent apoptosis in EA cells. Proline peptidase D Homo sapiens