Title : Cycloheximide blocks insulin-like growth factor I but not somatostatin inhibition of growth hormone secretion.

Pub. Date : 1987 Apr

PMID : 2886202






3 Functional Relationships(s)
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1 Cycloheximide blocks insulin-like growth factor I but not somatostatin inhibition of growth hormone secretion. Cycloheximide insulin-like growth factor 1 Rattus norvegicus
2 The major finding is that cycloheximide, a protein synthesis inhibitor, blocks inhibition of GRF-stimulated growth hormone release caused by IGF-I, without changing the inhibition caused by somatostatin. Cycloheximide insulin-like growth factor 1 Rattus norvegicus
3 Cycloheximide (15 micrograms/mL) totally blocked the effect of IGF-I but not somatostatin. Cycloheximide insulin-like growth factor 1 Rattus norvegicus