Title : Effect of zileuton on osteoporotic bone and its healing, expression of bone, and brain genes in rats.

Pub. Date : 2018 Jan 1

PMID : 28860177






2 Functional Relationships(s)
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1 An anti-inflammatory drug, zileuton (which is an inhibitor of arachidonate 5-lipoxygenase), is known to have a positive effect on bone tissue repair and brain ischemia. zileuton arachidonate 5-lipoxygenase Rattus norvegicus
2 NEW & NOTEWORTHY Zileuton, a 5-lipoxygenase inhibitor, increased bone volume, callus and cortical volume in osteotomized tibia, and trabecular and cortical volume in femur. zileuton arachidonate 5-lipoxygenase Rattus norvegicus