Title : The significance of aryl acylamidase activity of acetylcholinesterase in osteoblast differentiation and mineralization.

Pub. Date : 2018 Mar

PMID : 28852920






1 Functional Relationships(s)
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1 Inhibition of both the catalytic activities of AChE with edrophonium significantly reduced the amount of mineralization by decreasing the alkaline phosphatase (ALP) activity and expression of differentiation-related genes such as RUNX-2, COL1A, ALP, OC, and OP significantly (p < 0.05). Edrophonium acetylcholinesterase (Cartwright blood group) Homo sapiens