Title : Effect of CYP3A4*22, CYP3A5*3, and CYP3A combined genotypes on tamoxifen metabolism.

Pub. Date : 2017 Dec

PMID : 28849250






1 Functional Relationships(s)
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1 CYP3A5*3 marginally improved the explained variability of the (log transformed) metabolic ratio 4-hydroxy-tamoxifen/endoxifen (from 44.9 to 46.2%, p < 0.038). 4'-hydroxytamoxifen cytochrome P450 family 3 subfamily A member 5 Homo sapiens