Pub. Date : 2017 Oct
PMID : 28846937
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation. | BTYNB | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | The small molecule, BTYNB, was identified as a potent and selective inhibitor of IMP1 binding to c-Myc mRNA. | BTYNB | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | BTYNB destabilizes c-Myc mRNA, resulting in downregulation of c-Myc mRNA and protein. | BTYNB | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 4 | BTYNB destabilizes c-Myc mRNA, resulting in downregulation of c-Myc mRNA and protein. | BTYNB | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 5 | With its ability to target c-Myc and to inhibit proliferation of difficult-to-target melanomas and ovarian cancer cells, and with its unique mode of action, BTYNB is a promising small molecule for further therapeutic evaluation and mechanistic studies. | BTYNB | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |