Title : A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation.

Pub. Date : 2017 Oct

PMID : 28846937






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A Novel IMP1 Inhibitor, BTYNB, Targets c-Myc and Inhibits Melanoma and Ovarian Cancer Cell Proliferation. BTYNB insulin like growth factor 2 mRNA binding protein 1 Homo sapiens
2 The small molecule, BTYNB, was identified as a potent and selective inhibitor of IMP1 binding to c-Myc mRNA. BTYNB insulin like growth factor 2 mRNA binding protein 1 Homo sapiens
3 BTYNB potently inhibited proliferation of IMP1-containing ovarian cancer and melanoma cells with no effect in IMP1-negative cells. BTYNB insulin like growth factor 2 mRNA binding protein 1 Homo sapiens