Title : An amplified fluorescent aptasensor based on single-stranded DNA binding protein, copper and silica nanoparticles for sensitive detection of interferon-gamma.

Pub. Date : 2017 Sep 1

PMID : 28843559






2 Functional Relationships(s)
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1 The presences of double-stranded DNA (dsDNA) region and poly thymine (T) in the hairpin structure of the oligonucleotide, SSB and SNPs-streptavidin caused IFN-gamma determination with high selectivity and sensitivity. Oligonucleotides interferon gamma Homo sapiens
2 Upon addition of IFN-gamma, the hairpin structure of the oligonucleotide was disassembled and therefore, poly T strand interacted with SSB and a weak fluorescence signal was obtained. Oligonucleotides interferon gamma Homo sapiens