Title : Varenicline promotes endothelial cell migration by lowering vascular endothelial-cadherin levels via the activated α7 nicotinic acetylcholine receptor-mitogen activated protein kinase axis.

Pub. Date : 2017 Sep 1

PMID : 28842382






1 Functional Relationships(s)
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1 MLA (100nM), PD98059 (an ERK inhibitor; 20muM), SB203580 (a p38 inhibitor; 20muM) and SP600125 (a JNK inhibitor; 20muM) also blocked cell migration and varenicline-induced downregulation of VE-cadherin expression in HUVECs. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen-activated protein kinase 1 Homo sapiens