Pub. Date : 2017 Oct
PMID : 28836054
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Molecular study of ABCB1 gene and its correlation with imatinib response in chronic myeloid leukemia. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Three single-nucleotide polymorphisms (C1236T, G2677T/A, C3435T) and/or mRNA expression changes of ABCB1 gene were demonstrated to be associated with inter-individual variability of imatinib response in CML patients. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | In this study, we aimed to examine whether genetic variations and/or altered expression of ABCB1 gene may influence response to imatinib. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | CONCLUSION: Furthermore, analyses of ABCB1 haplotypes should be taken into account to study the relationship between ABCB1 genotypes and imatinib efficacy. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | CONCLUSION: Furthermore, analyses of ABCB1 haplotypes should be taken into account to study the relationship between ABCB1 genotypes and imatinib efficacy. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |