Title : Methylated polycyclic aromatic hydrocarbons and/or their metabolites are important contributors to the overall estrogenic activity of polycyclic aromatic hydrocarbon-contaminated soils.

Pub. Date : 2018 Feb

PMID : 28834568






1 Functional Relationships(s)
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1 The aryl hydrocarbon receptor antagonist/CYP1A1 inhibitor alpha-naphthoflavone decreased luciferase induction and EROD activity by several compounds, including the methylated chrysenes, suggesting that metabolites of these chemicals contributed to ER activation. alpha-naphthoflavone cytochrome P450 family 1 subfamily A member 1 Homo sapiens