Title : The Cytochrome P450 Enzyme Responsible for the Production of (Z)-Norendoxifen in vitro.

Pub. Date : 2018 Jan

PMID : 28834279






1 Functional Relationships(s)
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1 One micromolar ketoconazole (CYP3A inhibitor) showed an inhibitory effect on the rates of norendoxifen formation by 45%, but 1 mum quinidine (CYP2D6 inhibitor) does not show any inhibitory effect. Ketoconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens