Title : TP53 Mutational Status and ROS Effect the Expression of the Survivin-Associated Radio-Adaptive Response.

Pub. Date : 2017 Nov

PMID : 28813624






2 Functional Relationships(s)
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1 All mixed confluent cultures expressed enhanced radio-sensitization (P <= 0.047) characteristic of TP53 Mut cells, which could be inhibited by their exposure to the antioxidant N-acetyl-l-cysteine (NAC) indicating a role for intercellular signaling by reactive oxygen species (ROS). Reactive Oxygen Species tumor protein p53 Homo sapiens
2 All mixed confluent cultures expressed enhanced radio-sensitization (P <= 0.047) characteristic of TP53 Mut cells, which could be inhibited by their exposure to the antioxidant N-acetyl-l-cysteine (NAC) indicating a role for intercellular signaling by reactive oxygen species (ROS). Reactive Oxygen Species tumor protein p53 Homo sapiens