Pub. Date : 2017
PMID : 28811832
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) were reported to increase adiponectin by previous studies using a mixture of them. | Eicosapentaenoic Acid | adiponectin, C1Q and collagen domain containing | Homo sapiens |
| 2 | Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) were reported to increase adiponectin by previous studies using a mixture of them. | Eicosapentaenoic Acid | adiponectin, C1Q and collagen domain containing | Homo sapiens |
| 3 | In the present study, we observed and compared the individual effect of DHA and EPA on adiponectin in 3T3-L1 adipocytes, and further tested whether DHA or EPA regulated adiponectin by peroxisome proliferator-activated receptor gamma (PPARgamma) and its phosphorylation at Ser273 to provide a plausible explanation for their distinct actions. | Eicosapentaenoic Acid | adiponectin, C1Q and collagen domain containing | Homo sapiens |
| 4 | Adiponectin expressions in DHA treated groups were significantly higher than those in EPA treated groups at 50 and 100 mumol/L. | Eicosapentaenoic Acid | adiponectin, C1Q and collagen domain containing | Homo sapiens |
| 5 | GW9662 blocked DHA- and EPA-induced increases in PPARgamma as well as adiponectin. | Eicosapentaenoic Acid | adiponectin, C1Q and collagen domain containing | Homo sapiens |
| 6 | CONCLUSION: DHA compared with EPA led to a greater increase in cellular and secreted adiponectin at relative low concentrations by increasing PPARgamma expression and inhibiting its phosphorylation at Ser273. | Eicosapentaenoic Acid | adiponectin, C1Q and collagen domain containing | Homo sapiens |