Pub. Date : 2017 Oct 15
PMID : 28807941
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | This review examines the multiple mechanisms leading to Rac1 hyperactivation, particularly focusing on emerging paradigms that involve gain-of-function mutations in Rac and guanine nucleotide exchange factors, defects in Rac1 degradation, and mislocalization of Rac signaling components. | Guanine Nucleotides | Rac family small GTPase 1 | Homo sapiens |