Pub. Date : 2017 Nov
PMID : 28807879
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Apigenin-induced ABCC1-mediated efflux of glutathione from mature erythrocytes inhibits the proliferation of Plasmodium falciparum. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 2 | In this report, it was of interest to perturb the redox homeostasis of normal erythrocytes through drug-induced active efflux of glutathione via erythrocyte ABCC1, a member of the C-subfamily of the human ATP-binding cassette (ABC) transporters. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |
| 3 | To achieve this objective, we made use of apigenin (API), shown previously to activate ABCC1 glutathione efflux in mature erythrocytes. | Glutathione | ATP binding cassette subfamily C member 1 | Homo sapiens |