Title : Olaparib protects cardiomyocytes against oxidative stress and improves graft contractility during the early phase after heart transplantation in rats.

Pub. Date : 2018 Jan

PMID : 28806493






1 Functional Relationships(s)
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1 KEY RESULTS: Olaparib blocked autoPARylation of PARP1 and attenuated the rapid onset of death in H9c2 cells, induced by H2 O2 , but did not affect cell death following chronic, prolonged oxidative stress induced by GOx. olaparib poly (ADP-ribose) polymerase 1 Rattus norvegicus