Title : Schisandrin B attenuates CCl4-induced liver fibrosis in rats by regulation of Nrf2-ARE and TGF-β/Smad signaling pathways.

Pub. Date : 2017

PMID : 28794616






3 Functional Relationships(s)
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Protein Name
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1 Schisandrin B attenuates CCl4-induced liver fibrosis in rats by regulation of Nrf2-ARE and TGF-beta/Smad signaling pathways. schizandrin B transforming growth factor, beta 1 Rattus norvegicus
2 In an in vitro study, it was shown that Sch B inhibited TGF-beta-induced HSC activation. schizandrin B transforming growth factor, beta 1 Rattus norvegicus
3 This study demonstrates that Sch B prevents the progression of liver fibrosis by the regulation of Nrf2-ARE and TGF-beta/Smad signaling pathways, and indicates that Sch B can be used for the treatment of liver fibrosis. schizandrin B transforming growth factor, beta 1 Rattus norvegicus