Title : Development of tolerance to glyceryl trinitrate in an isolated human peripheral vein and its relation to cyclic GMP metabolism.

Pub. Date : 1986 Aug

PMID : 2877539






2 Functional Relationships(s)
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1 Development of tolerance to glyceryl trinitrate in an isolated human peripheral vein and its relation to cyclic GMP metabolism. Nitroglycerin 5'-nucleotidase, cytosolic II Homo sapiens
2 The relaxant activity as well as the level of intracellular cyclic GMP were restored in GTN-tolerant vessels by dipyridamole (5 microM), an agent with phosphodiesterase inhibiting properties. Nitroglycerin 5'-nucleotidase, cytosolic II Homo sapiens