Title : Impaired CBS-H2S signaling axis contributes to MPTP-induced neurodegeneration in a mouse model of Parkinson's disease.

Pub. Date : 2018 Jan

PMID : 28774789






3 Functional Relationships(s)
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1 Interestingly, among the three H2S generating enzymes, only cystathionine beta-synthase (CBS) expression was largely reduced in the striatum of MPTP-treated mice. Deuterium cystathionine beta-synthase Mus musculus
2 Interestingly, among the three H2S generating enzymes, only cystathionine beta-synthase (CBS) expression was largely reduced in the striatum of MPTP-treated mice. Deuterium cystathionine beta-synthase Mus musculus
3 Taken together, our data suggest that impaired CBS-H2S axis may contribute to the pathogenesis of PD, and that modulation of this axis may become a novel therapeutic approach for PD. Deuterium cystathionine beta-synthase Mus musculus