Title : Inhibiting ERK/Mnk/eIF4E broadly sensitizes ovarian cancer response to chemotherapy.

Pub. Date : 2018 Mar

PMID : 28766096






1 Functional Relationships(s)
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1 RESULTS: Increased phosphorylation levels of ERK, Mnk1, and eIF4E were observed in ovarian cancer cell exposed to chemotherapeutic agents, and paclitaxel-resistant SK-OV-3-r cells, and is a common response of ovarian cancer patients undergoing chemotherapy. Paclitaxel mitogen-activated protein kinase 1 Homo sapiens