Title : Capsaicin-induced rapid neutrophil leukocyte activation in the rat urinary bladder microcirculatory bed.

Pub. Date : 2018 Feb

PMID : 28762564






2 Functional Relationships(s)
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1 CONCLUSIONS: Topical application of capsaicin induces early neurogenically mediated cellular microcirculatory inflammatory reactions via the activation of the TRPV1 receptor and the release of CGRP and SP from sensory nerves in the bladder. Capsaicin calcitonin-related polypeptide alpha Rattus norvegicus
2 Co-administration of SP and CGRP receptor antagonists may ameliorate microcirculatory inflammatory changes elicited by capsaicin in the urinary bladder. Capsaicin calcitonin-related polypeptide alpha Rattus norvegicus