Title : Combination therapy with ampicillin and azithromycin improved outcomes in a mouse model of group B streptococcal sepsis.

Pub. Date : 2017

PMID : 28759625






2 Functional Relationships(s)
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1 METHODS: TNF-alpha was measured from supernatants of RAW 264.7 cells stimulated with GBS isolates, in presence of four treatment regimens: ampicillin alone, azithromycin alone, or combination of azithromycin plus ampicillin. Azithromycin tumor necrosis factor Mus musculus
2 RESULTS: GBS isolates exposed to azithromycin or combination (compared to ampicillin alone) stimulated less TNF production in vitro. Azithromycin tumor necrosis factor Mus musculus