Title : Experimental study on the apoptosis of cervical cancer Hela cells induced by juglone through c-Jun N-terminal kinase/c-Jun pathway.

Pub. Date : 2017 Jun

PMID : 28756921






2 Functional Relationships(s)
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1 In cells treated with 40 mumol/L juglone and SP600125, the protein expressions of Bax, CytC, Fas, FasL and Caspase-3 were significantly lower than those of cells treated with 40 mumol/L juglone (P < 0.05), and the protein expressions of Bax, CytC, Fas, FasL and Caspase-3 reduced more remarkably as the SP600125 dosage increased (P < 0.05). pyrazolanthrone BCL2 associated X, apoptosis regulator Homo sapiens
2 In cells treated with 40 mumol/L juglone and SP600125, the protein expressions of Bax, CytC, Fas, FasL and Caspase-3 were significantly lower than those of cells treated with 40 mumol/L juglone (P < 0.05), and the protein expressions of Bax, CytC, Fas, FasL and Caspase-3 reduced more remarkably as the SP600125 dosage increased (P < 0.05). pyrazolanthrone BCL2 associated X, apoptosis regulator Homo sapiens