Pub. Date : 2017 Sep 15
PMID : 28755973
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | l-Cysteine supplementation increases insulin sensitivity mediated by upregulation of GSH and adiponectin in high glucose treated 3T3-L1 adipocytes. | Glutathione | insulin | Homo sapiens |
| 2 | This study examined the hypothesis that LC supplementation positively up regulates the effects of insulin on GSH and glucose metabolism in 3T3-L1 adipocyte model. | Glutathione | insulin | Homo sapiens |
| 3 | Treatment with insulin alone significantly (p < 0.05) reduced ROS levels as well as increased DsbA-L, adiponectin, GCLC, GCLM, GSH, and GLUT-4 protein levels, glucose utilization, and improved total and HMW adiponectin secretion in HG treated adipocytes compared to HG alone. | Glutathione | insulin | Homo sapiens |
| 4 | In addition, LC supplementation along with insulin increased GCLC (21% Vs LC, 14% insulin), GCLM (28% Vs LC, 16% insulin) and GSH (25% Vs LC and insulin) levels compared with the either insulin or LC alone in HG-treated cells. | Glutathione | insulin | Homo sapiens |