Title : Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK293 cells.

Pub. Date : 2017 Dec

PMID : 28755515






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Bufalin, a bufanolide steroid from the parotoid glands of the Chinese toad, suppresses hERG K+ currents expressed in HEK293 cells. bufalin ETS transcription factor ERG Homo sapiens
2 In this study, we investigated the effect of bufalin on the human ether-a-go-go-related gene (hERG) K+ channels using the perforated patch recording technique. bufalin ETS transcription factor ERG Homo sapiens
3 These findings suggest that bufalin is a potent hERG K+ channel blocker and may provide a new way for understanding Chan Su-induced arrhythmia. bufalin ETS transcription factor ERG Homo sapiens